Siglec-8 antibody
WebAlexa Fluor™ 555-Labeled Human Siglec-2 / CD22 Protein, His TagStar Staining 400-682-2521 [email protected] 注册 登录 登录 注册 关注公众号
Siglec-8 antibody
Did you know?
Consistent with the role of most siglecs and the presence of the intracellular ITIM, Siglec-8 has been found to function as an inhibitory immunoregulatory receptor. Ligation of Siglec-8 induces cell death in eosinophils, and, surprisingly, the normally pro-survival cytokines interleukin (IL)-5 and GM-CSF have been found to potentiate this cell death effect. IL-33, which activates and maintains eosinophils, also exerts a similar potentiating effect on Siglec-8-induced cell death. Inhibitor stud… WebLatest Publications for our SIGLEC8 Antibodies Youngblood, Brock, Leung, Falahati, Bochner, Rasmussen, Peterson, Bebbington, Tomasevic: "Siglec-8 antibody reduces ...
WebSialic acid–binding immunoglobulin-like lectin 8 (Siglec-8) is an inhibitory receptor that is selectively expressed on mature eosinophils and mast cells, with low expression on … WebTarget Information. SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-linked sialic acid. and also …
WebApr 14, 2024 · Within the ECD, human Siglec10 is most closely related to Siglec5 (42% aa sequence identity). It shares 63% aa sequence identity with mouse SiglecG. Siglec10 is expressed on eosinophils, neutrophils, monocytes, and B cells (5, 8) with some splice variants predominating in WebSiglec-8 Antibody. NBP1-06078 is a primary antibody from Novus Biologicals. 2 Citations Host: Goat Clonality: Polyclonal Validations: None Available Applications: WB and ELISA. …
WebOct 22, 2024 · More information: Evan S. Dellon et al. Anti–Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis, New England Journal of Medicine (2024). DOI: …
WebAnti-SIGLEC8 antibodies are offered by a number of suppliers. This target gene encodes the protein 'sialic acid binding Ig like lectin 8' in humans and may also be known as Siglec-8, … explaining experiences for jobWebThis assay employs an antibody specific for Human Siglec-1 coated on a 96-well PCR plate. Standards and samples are pipetted into the wells and Siglec-1 present in a sample is bound to the wells by the immobilized antibody. ... May be stored for up to 6 months at 2° to 8°C from the date of shipment. b\u0026m homestores onlineWebThe Recombinant Human Siglec-10 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human Siglec-10 Fc Chimera Protein has been validated for the following applications: Binding Activity.Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture … b\u0026m hr contact numberWebMouse Anti-SIGLEC8 Recombinant Antibody (CBXS-3127) - This product is a mouse antibody that recognizes SIGLEC8. The antibody CBXS-3127 can be used for immunoassay techniques such as: ... SIGLEC-8; SAF-2; SAF2; Sialic Acid Binding Ig-Like Lectin 8; Sialic Acid-Binding Ig-Like Lectin 8; SIGLEC8L; CDw329; Function. explaining empathyWebMonoclonal Anti-Siglec-10 antibody produced in mouse. clone 1D11, purified immunoglobulin, buffered aqueous solution. View Price and Availability. Z189006. Ace … b \u0026 m housewaresWebJun 15, 2024 · A humanized antibody, AK002, targeting Siglec-8 is undergoing development for treatment of diseases associated with mast cell and eosinophil-driven inflammation. … b\u0026m hull city centreWebView 11 Siglec-8 Primary Antibodies. Bio-Techne offers high-quality reagents instruments, custom manufacturing, and testing services. b\u0026m hot tub accessories